diff --git a/ci/test-matrix.yml b/ci/test-matrix.yml
index 34128d4fd35..296c8f19acc 100644
--- a/ci/test-matrix.yml
+++ b/ci/test-matrix.yml
@@ -57,7 +57,9 @@ linux:
     - { ARCH: 'amd64', PY_VER: '3.14t', CUDA_VER: '12.9.1', LOCAL_CTK: '1', GPU: 't4',         GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'amd64', PY_VER: '3.14t', CUDA_VER: '13.0.2', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'amd64', PY_VER: '3.14t', CUDA_VER: '13.4.2', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'amd64', PY_VER: '3.15',  CUDA_VER: '12.9.1', LOCAL_CTK: '0', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'amd64', PY_VER: '3.15',  CUDA_VER: '13.4.2', LOCAL_CTK: '0', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'amd64', PY_VER: '3.15t',  CUDA_VER: '12.9.1', LOCAL_CTK: '0', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'amd64', PY_VER: '3.15t', CUDA_VER: '13.4.2', LOCAL_CTK: '0', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     # linux-aarch64
     - { ARCH: 'arm64', PY_VER: '3.11',  CUDA_VER: '12.9.1', LOCAL_CTK: '0', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
@@ -76,6 +78,10 @@ linux:
     - { ARCH: 'arm64', PY_VER: '3.14t', CUDA_VER: '12.9.1', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'arm64', PY_VER: '3.14t', CUDA_VER: '13.0.2', LOCAL_CTK: '0', GPU: 'a100',       GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'arm64', PY_VER: '3.14t', CUDA_VER: '13.4.2', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'arm64', PY_VER: '3.15', CUDA_VER: '12.9.1', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'arm64', PY_VER: '3.15', CUDA_VER: '13.4.2', LOCAL_CTK: '1', GPU: 'a100',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'arm64', PY_VER: '3.15t', CUDA_VER: '12.9.1', LOCAL_CTK: '1', GPU: 'a100',         GPU_COUNT: '1', DRIVER: 'latest' }
+    - { ARCH: 'arm64', PY_VER: '3.15t', CUDA_VER: '13.4.2', LOCAL_CTK: '1', GPU: 'l4',         GPU_COUNT: '1', DRIVER: 'latest' }
     # special runners
     - { ARCH: 'amd64', PY_VER: '3.13',  CUDA_VER: '13.0.2', LOCAL_CTK: '1', GPU: 'h100',       GPU_COUNT: '1', DRIVER: 'latest' }
     - { ARCH: 'amd64', PY_VER: '3.13',  CUDA_VER: '13.4.2', LOCAL_CTK: '1', GPU: 'h100',       GPU_COUNT: '1', DRIVER: 'latest' }
diff --git a/cuda_bindings/pyproject.toml b/cuda_bindings/pyproject.toml
index c9147a28e8a..59ebdf93f78 100644
--- a/cuda_bindings/pyproject.toml
+++ b/cuda_bindings/pyproject.toml
@@ -45,8 +45,7 @@ all = [
 test = [
     "cython>=3.2.5,<3.3",
     "setuptools>=80.0.0",
-    # <=2.6.0.dev0 admits scientific-python nightlies (for Python 3.15)
-    "numpy>=1.21.1,<=2.6.0.dev0",
+    "numpy>=1.21.1",
     "pytest==9.1.0",
     "pytest-benchmark==5.2.3",
     "pytest-repeat==0.9.4",
diff --git a/cuda_core/pyproject.toml b/cuda_core/pyproject.toml
index 588e751fe5f..53abf9bf308 100644
--- a/cuda_core/pyproject.toml
+++ b/cuda_core/pyproject.toml
@@ -81,8 +81,7 @@ test = [
     "pyglet==2.1.14",
     "cffi==2.1.1",
 ]
-# TODO: drop the Windows 3.15 guard once ml-dtypes publishes cp315 Windows wheels
-ml-dtypes = ["ml-dtypes>=0.5.4,<0.6.0; sys_platform != 'win32' or python_version < '3.15'"]
+ml-dtypes = ["ml-dtypes>=0.5.4"]
 test-ft = ["pytest-run-parallel==0.10.0"]
 test-cu12 = [ {include-group = "ml-dtypes" }, {include-group = "test" }, "cupy-cuda12x; python_version < '3.15'", "cuda-toolkit[cudart]==12.*"]  # runtime headers needed by CuPy
 test-cu13 = [ {include-group = "ml-dtypes" }, {include-group = "test" }, "cupy-cuda13x; python_version < '3.15'", "cuda-toolkit[cudart]==13.*"]  # runtime headers needed by CuPy