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Cell State Prediction in Disease Progression

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🧬 Cell State Prediction in Disease Progression

📖 Project Overview

Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of cellular behavior in diseases such as cancer, neurodegenerative disorders, and inflammatory diseases. This project leverages transformer-based models (scGPT, scVI) to predict cell state transitions during disease progression.

🔍 Key Features:

  • ✅ Preprocess and normalize scRNA-seq data.
  • ✅ Train transformer-based models (scGPT, scVI) to predict cell states.
  • ✅ Compare predictions with traditional methods (Monocle3, PAGA).
  • ✅ Deploy an interactive web application for visualization.

📂 Project Structure

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