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@cxbl-gbu

CxBL - Computational and Experimental Biomolecular Lab

🧬 CxBL — Computational & Experimental Biomolecular Lab

Gujarat Biotechnology University, Gandhinagar, India

CxBL is a research group working at the intersection of computational biology, protein design & engineering, structural bioinformatics, and artificial intelligence/machine learning.

Our research focuses on understanding and engineering biomolecular systems using sequence-, structure-, and dynamics-based approaches.

🔬 Research Areas

  • Protein Design & Engineering
  • AI/ML for Biomolecular Science
  • Protein Structure Prediction & Analysis
  • Molecular Modelling & Molecular Dynamics
  • Protein Stability & Thermostability Engineering
  • Protein–Protein and Protein–Ligand Interactions
  • Computational Genomics & Bioinformatics
  • Development of Computational Biology Tools and Workflows

We combine AI-based prediction, molecular modelling, simulation, and experimental validation to study and engineer proteins and other biomolecular systems.

🧠 Our Approach

Sequence → Structure → Dynamics → AI/ML → Design → Validation

🚀 Mission

To develop AI-driven and physics-informed computational approaches for biomolecular design and engineering, and translate computational predictions into experimentally testable biological systems.

🔗 Explore our repositories: https://github.com/cxbl-gbu

Popular repositories Loading

  1. GUI_unidock GUI_unidock Public

    HTML

  2. NirA_DeepDocking NirA_DeepDocking Public

    Forked from vedasoham/NirA_DeepDocking

    Python

  3. boltz2-notebook boltz2-notebook Public

    Forked from AtharvaTilewale/boltz2-notebook

    Boltz2 Notebook – A streamlined Colab-based pipeline for protein structure prediction and binding affinity analysis using the Boltz2 deep learning model.

    HTML

  4. FELBuilder FELBuilder Public

    Forked from AtharvaTilewale/FELBuilder

    FELBuilder is an automated Python pipeline that automates the complex workflow of Principal Component Analysis (PCA) and Free Energy Landscape (FEL) analysis from Molecular Dynamics (MD) trajectories.

    Python

  5. GRAVITy GRAVITy Public

    Forked from AtharvaTilewale/GRAVITy

    GRAVITy is an automated pipeline that streamlines molecular dynamics (MD) simulations. It allows users to simulate protein efficiently. It automates tasks like protein preparation, running simulati…

    Shell

  6. TargetX TargetX Public

    TargetX is an automated bioinformatics pipeline designed to rapidly screen potential drug targets from an extensive bacterial dataset. TargetX uses a systemic "negative-to-positive" filtering strat…

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