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Chrcov - #17

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csoneson merged 14 commits into
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chrcov
Sep 25, 2026
Merged

csoneson merged 14 commits into
develfrom
chrcov

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mbstadler and others added 13 commits September 22, 2026 14:29
Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
New method 'simple' ignores CIGAR strings and covers the whole reference
span between the first and last aligned position of each alignment
(via htslib's bam_endpos), so soft-clip and inserted bases also count
as covered. 'full' remains the default and is unchanged. Benchmark on
a 102 GB Dorado 6mA BAM (GRCm39, ~100x): simple is ~1.2x faster on a
1 Mb region and roughly tied at 10-100 Mb, so the win is modest for
long ONT reads.

Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
Co-authored-by: Charlotte Soneson <charlottesoneson@gmail.com>
Co-authored-by: Michael Stadler <stadler.michael@gmail.com>
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codecov Bot commented Sep 25, 2026 •

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Codecov Report

✅ All modified and coverable lines are covered by tests.
✅ Project coverage is 99.97%. Comparing base (cc8ebc3) to head (5d8bee9).
⚠️ Report is 15 commits behind head on devel.

Additional details and impacted files
@@           Coverage Diff            @@
##            devel      #17    +/-   ##
========================================
  Coverage   99.97%   99.97%            
========================================
  Files          31       31            
  Lines        3832     3951   +119     
========================================
+ Hits         3831     3950   +119     
  Misses          1        1            

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@csoneson
csoneson merged commit 1148145 into devel Sep 25, 2026
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@csoneson
csoneson deleted the chrcov branch September 25, 2026 07:39
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2 participants