genepi-freiburg

R package to facilitate genetic colocalization analysis.

Two-sample Mendelian randomization of 10 dietary components on kidney function (eGFR, CKD). IEU OpenGWAS instruments, automated PheWAS + Steiger screening + G-EE appraisal, MVMR, sensitivity analyses, and FinnGen R12 validation

Systematic review of rare-variant phenome-wide association studies (PheWAS) using WES/WGS data — methodology comparison across 26 studies plus PKD1 cross-study consistency analysis.

preprocessing pipeline for DNA methylation data from Infinium 450k and EPIC arrays

CellMatchR Shinylive web app

Scripts for performing decentral GWAS and central QC in a Consortium setting